HVLD

High-Voltage Leak Detection (HVLD) for Container Closure Integrity Testing in Pharmaceutical Packaging

Container Closure Integrity Testing (CCIT) is a critical quality assurance activity in the pharmaceutical industry, particularly for sterile injectable and parenteral drug products. High-Voltage Leak Detection (HVLD) has emerged as a deterministic, non-destructive technology capable of detecting micro-defects in non-conductive pharmaceutical containers filled with electrically conductive liquids. This article reviews Read more

By nordtest, ago

65th Simposio AFI

We will be present at the 65th Simposio AFI (Association of Pharma Industries). Join us! Date: 10th-11th-12th June 2026 Booth: 137 Place: Palacongressi di Rimini, Via della Fiera, 23, 47923 Rimini (RN) ITALY Link: https://simposio.afiscientifica.it/

By nordtest, ago

64th AFI Symposium

We will be present at the 64th AFI Symposium (Association of Pharma Industries). Join us! Date: 11th-12th-13th June 2025 Booth: 137 Place: Palacongressi di Rimini, Via della Fiera, 23, 47923 Rimini (RN) ITALY Link: https://simposio.afiscientifica.it/

By nordtest, ago

Container Closure Integrity Testing (CCIT) under GMP Annex 1: Guidelines and Best Practices

Ensuring container closure integrity (CCI) is a fundamental requirement for sterile pharmaceutical products to prevent contamination and maintain product stability. The revised EU Good Manufacturing Practice (GMP) Annex 1, which provides detailed guidance on the manufacture of sterile medical products, emphasizes the necessity of container closure integrity testing (CCIT) throughout Read more

By nordtest, ago

HVLD High Voltage Leak Test

Among the different techniques for Deterministic Leak Test procedures, one of the most interesting and effective is the HVLD High Voltage Leak Test. This method is known and applied for many years, at least from the early 70ies of last century, but originally it has been developed for application in Read more

By nordtest, ago